![]() Measurements were performed on polymeric NPs, as these represent one of the major classes of NPs under development for drug-delivery aims. Each analysis was accomplished in 2 min, rendering a determination throughput of 30 h –1 (6 samples h –1 for n = 5) and only requiring 30 μL (≈0.03 g) of NPs suspension. NPs concentration measurements were based on the decrease in the light transmitted to the detector due to the light scattered by NPs when passing through the optical path. Automatic NPs sampling and delivery to the LOV detection unit were set by flow programming. Herein, a miniaturized automated ensemble method to measure NPs concentration was established under the lab-on-valve (LOV) mesofluidic platform. Still, faster and simpler procedures, dismissing skilled operators and post-analysis conversions are needed to quantify NPs for research and quality control operations, and to support result validation. ![]() The evaluation of this parameter is required during NPs developmental and quality control stages, for setting dose–response correlations and for evaluating the reproducibility of the manufacturing process. Chapters are to be found on multicomponent mixtures, polyelectrolytes, dense polymer systems, gels, rigid rods, micellar systems and the application of dynamic light scattering to biological systems.ġ:Dynamic scattering from multicomponent polymer mixtures in solution and in bulkģ:Noise on photon correlation functions and its effects on data reduction algorithmsĤ:Data analysis in dynamic light scatteringĥ:Dynamic light scattering and linear viscoelasticity of polymers in solution and in the bulkĦ:Dynamic properties of polymer solutionsħ:Application of dynamic light scattering to polyelectrolytes in solutionĨ:Simultaneous static and dynamic light scattering: application to polymer structure analysisĩ:Dynamic light scattering from dense polymer systemsġ0:Dynamic light scattering from polymers in solution and in bulkġ1:Dynamic light scattering from polymer gelsġ2:Dynamic light scattering from rigid and nearly rigid rodsġ4:Critical dynamics of binary liquid mixtures and simple fluids studied using dynamic light scatteringġ5:Application of dynamic light scattering to biological systemsNanoparticles (NPs) concentration directly impacts the dose delivered to target tissues by nanocarriers. The second aim is to illustrate the widely varying fields in which the technique finds application. Theoretical developments relating dynamic light scattering to the viscoelasticity of polymers in solution and in the bulk are described. This volume is directed in part to the philosophy and current practice in dynamic light scattering: single photon correlation techniques are introduced, a discussion of noise on photon correlation functions is given and data analysis in dynamic light scattering to polymer structure analysis is presented and a comprehensive introduction to diffusing wave spectroscopy is given. ![]() It can be employed on extremely small fluid volumes, the instrumentation is relatively inexpensive and allows the rapid determination of diffusion coefficients as well as providing information on relaxation time distributions for the macromolecular components of complex systems. The importance of the technique lies in its non-invasive character. Oxford Research Encyclopedias: Global Public Healthĭynamic light scattering is a new method for investigating macromolecular systems.The European Society of Cardiology Series.Oxford Commentaries on International Law. ![]()
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